After losing Vanessa (Morena Baccarin), the love of his life, fourth-wall-breaking mercenary Wade Wilson, aka Deadpool (Ryan Reynolds), must assemble a team and protect a young mutant Russell Collins, aka Firefist (Julian Dennison), from Cable (Josh Brolin), a no-nonsense, dangerous cyborg from the future, and must also learn the most important lesson of all: to be part of a family again.